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Signs of premature aging are rare symptoms of Werner syndrome



Werner syndrome is a rare genetic disorder characterized by rapid aging that begins in early adolescence or young adulthood. It is also called progeria, according to the Times of India.

Werner syndrome is characterized by the rapid onset of features associated with normal aging. People with this disorder usually grow normally into adulthood.

Signs associated with dramatic aging usually begin to develop when they are in their twenties.

Werner syndrome symptoms

Signs and symptoms associated with Werner syndrome include:

Graying and hair loss

-hoarse voice

Thin and firm skin

Thin arms and legs

Unusual facial features

Health complications of Werner syndrome

As Werner syndrome progresses, individuals may develop health complications associated with aging early in life, including cataracts, skin ulcers, severe hardening of the arteries, diabetes, osteoporosis (thinning of the bones), and fertility problems.

People with Werner syndrome have an increased risk of cancer - especially thyroid cancer, melanoma, and sarcoma (a type of bone or soft tissue cancer). Individuals with Werner syndrome usually live into their late 40s or early 50s. The most common causes of death include cancer and sclerosis. arteries.

Is Werner syndrome hereditary

Werner syndrome is inherited in an autosomal recessive pattern. This means that both copies of the WRN gene in each cell have mutations. The WRN gene provides instructions for the production of Werner protein. This protein helps perform several tasks related to DNA maintenance and repair.

What causes Werner syndrome

Scientists aren't entirely sure how WRN mutations cause symptoms of Werner syndrome.

  It is thought that cells with the altered Werner protein may divide more slowly or stop dividing earlier than normal. This may lead to problems with growth. The altered protein may allow DNA damage to build up, which can impair normal cell activities and lead to the health problems associated with this condition.

Is there a cure for Turner syndrome

There is no adequate treatment for Werner syndrome, but treatment involves a multidisciplinary team.

Cataracts can be treated with surgery. Physical exams can help check for skin ulcers, diabetes, malignancy, or cardiovascular disease. Malignant tumors can be treated with surgery, chemotherapy or radiation, and it is advised to avoid smoking and lead a healthy lifestyle - including regular exercise and a low-fat diet.

Psychological counseling can also help provide support to patients with Werner syndrome, as well as to their family members.

What are the health problems associated with aging

Old age is often accompanied by some medical problems such as osteoporosis or arthritis and high blood pressure. It is usually confused and not distinguished between aging and dementia or Alzheimer's, which are considered one of the health problems associated with aging, and their symptoms may be similar to the symptoms of aging, but this does not mean that everyone who has advanced in age and has reached the stage of aging will suffer from dementia and Alzheimer's.

The chances of developing the following diseases increase among people in old age:

heart disease.






What are the physiological changes associated with aging

The physiological effects of aging differ from one person to another, but there is something in common between these effects, such as the incidence of chronic diseases more than acute diseases, and among the changes that occur in old age, we mention the following:

Cardiovascular: The blood vessels and arteries may begin to harden, which increases the effort of the heart to pump blood. This may cause the heart muscles to change to adapt to the increased workload. These changes may increase the risk of high blood pressure and cardiovascular disease.

Bones and joints: With age, bones tend to shrink in size and density, which leads to weakness and an increased chance of fracture. While the muscles lose their flexibility, strength and endurance, which affects coordination and balance.

Digestive system: Structural changes in the large intestine with age increase the chance of constipation, and some factors may increase constipation, such as decreased activity, lack of exercise, lack of fluids, and a low-fiber diet, and some pharmacological treatments such as diuretics and supplementation Iron and some diseases such as diabetes increase the chance of constipation.

Urinary tract: The bladder becomes less elastic, which increases the need to urinate. Weakness of the bladder muscles also occurs, which means difficulty in emptying the bladder completely, or loss of control and urinary incontinence.

Eyes: aging affects the lens of the eye and leads to blurred vision and cataracts, increased sensitivity to light and difficulty in adjusting to different light levels, and

Ears: There is a decrease in the ability to hear, especially high waves or hearing speech in crowded rooms.

Mouth and teeth: Some medications, such as those for high blood pressure and diabetes, may cause dry mouth, which may increase the risk of tooth decay and gum and tooth infection.

Skin: The skin becomes less elastic, thicker and weaker, bruises easily, oil production in the skin decreases, the number of fatty tissues under the skin appears, and wrinkles, spots and skin growths appear.

Weight: The metabolic rate decreases in old age, which causes weight gain, especially if activity and movement decrease while eating remains at the same level.

Sexual health: Diseases and medications taken during aging affect sexual ability. Women may experience vaginal dryness, which reduces the ability to enjoy sex. Men may become impotence or weakness, which makes sex more difficult than before.

Plastic surgery media consultant, journalist since 2011, member of the Journalists Syndicate, member of the Medical Editors Division, Union of Arab Journalists. He writes in the field of health, skin care and relaxation.